Retin-A (tretinoin topical) can be recommended for patients diagnosed with acne that did not benefit from lifestyle modification. Most patients notice the benefits of applying Retin-A only after three to four weeks of the treatment. You will be supposed to apply it regularly and exactly as recommended by your health care provider for the first results to become obvious soon. Retin-A is usually applied using clean and dry hands. The area to which you are applying this medicine is also supposed to be clean (wash it with some mild soap) and dry. The skin must be dried with a soft towel and 20 minutes should pass before the application. You don't need to apply a thick layer of Retin-A - a thin layer that will cover the area affected will be sufficient. Retin-A is usually applied before going to bed, so make sure you remember about your applications and use Retin-A regularly for best effect. It's normal for the condition of your acne to get worse at first - but this means the treatment is actually working for you. Make sure you take Retin-A regularly for as long as recommended - you may need some three weeks to notice the first benefits of the treatment.
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